A person’s precise genetic makeup can significantly impact the way they respond to drugs, such as chemotherapy. Our scientists are uncovering genetic variants (differences in the DNA sequence) that differ among individuals and confer sensitivity or resistance to various chemotherapeutic agents, in terms of antitumor activity and the adverse effects they cause (called toxicities).
Big Data Initiatives at UChicago Medicine
The University of Chicago Medicine Comprehensive Cancer Center continues to lead national efforts in using cancer bioinformatics and cloud computing to get an in-depth view of cancer genomics, epigenetics, proteomics, and gene expression. These data are allowing cancer researchers to get an unprecedented glimpse into the inner workings of cancer and helping to identify promising molecular targets at an accelerated pace.
A person’s precise genetic makeup can significantly impact the way they respond to drugs, such as chemotherapy. Our scientists are uncovering genetic variants (differences in the DNA sequence) that differ among individuals and confer sensitivity or resistance to various chemotherapeutic agents, in terms of antitumor activity and the adverse effects they cause (called toxicities).